What does cholinesterase testing of the blood indicate?

Cholinesterase testing of the blood is primarily used to assess the functional status of the cholinesterase enzyme, which plays a crucial role in breaking down neurotransmitters in the body, particularly acetylcholine. In the context of pesticide exposure, particularly with organophosphate and carbamate pesticides, cholinesterase levels can decrease significantly due to the inhibitory effects of these chemicals on the enzyme.

When a pesticide applicator's cholinesterase levels are tested, a lower than normal level can indicate that the applicator has been exposed to these pesticides, demonstrating the pesticide's adverse effect on the body. The testing serves as a bio-indicator of exposure and whether the applicator may be experiencing physiological impacts due to pesticide absorption.

Understanding this relationship highlights the importance of regular monitoring for individuals who work with certain pesticides, to prevent serious health implications and ensure safe practices in pesticide application.